反应详情

N-phenylacetyl-D,L-leucyl-L-proline benzyl ester (2 g) was dissolved in methanol (40 ml), and 10% palladium-carbon (200 mg) was added. The resulting mixture aerated with hydrogen was allowed to react at room temperature for 3 h, filtered and concentrated under reduced pressure to remove the solvent to give a colourless sticky matter (1.55 g, 98%), which was directly used for the next reaction.

1. customto react at room temperature for 3 h
2. filtrationfiltered
3. concentrationconcentrated under reduced pressure
4. customto remove the solvent
5. customto give a colourless sticky matter (1.55 g, 98%), which
6. customwas directly used for the next reaction