HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 89800236, compound → HCID 89800333, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 89800236 | HCID 89800236 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 89800333 | HCID 89800333 | — |
Reaction Steps
N-phenylacetyl-D,L-leucyl-L-proline benzyl ester (2 g) was dissolved in methanol (40 ml), and 10% palladium-carbon (200 mg) was added. The resulting mixture aerated with hydrogen was allowed to react at room temperature for 3 h, filtered and concentrated under reduced pressure to remove the solvent to give a colourless sticky matter (1.55 g, 98%), which was directly used for the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09434760B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-dc6887c10f434b009b85da277eb38fe3 |
| Source note | uspto-grants-2016_09 |