反应详情

A mixture of 3.25 g of isatoic anhydride, 2.78 g of 3-(1H-imidazol-1-yl)butanamine and 40 ml of ethanol was stirred at room temperature for 20 hours and concentrated. The residue and 10 ml of triethyl orthoformate were heated at 95°-115° C. for 3 hours and concentrated to obtain the desired product as an oil.

1. concentrationconcentrated
2. temperatureThe residue and 10 ml of triethyl orthoformate were heated at 95°-115° C. for 3 hours
3. concentrationconcentrated