HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isatoic Anhydride → 3-[3-(1H-Imidazol-1-yl)butyl]-4(3H)-quinazolinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isatoic Anhydride | HCID 8359 | — |
| Reactant | 3-(1H-Imidazol-1-yl)butan-1-amine | HCID 13952862 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-[3-(1H-Imidazol-1-yl)butyl]-4(3H)-quinazolinone | HCID 14232977 | — |
Reaction Steps
A mixture of 3.25 g of isatoic anhydride, 2.78 g of 3-(1H-imidazol-1-yl)butanamine and 40 ml of ethanol was stirred at room temperature for 20 hours and concentrated. The residue and 10 ml of triethyl orthoformate were heated at 95°-115° C. for 3 hours and concentrated to obtain the desired product as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04753944 |
| Source dataset | uspto-grants-1988_06 |
| ORD ID | ord-97ec92b6b8884d02a10e2f3e06a3dc2a |
| Source note | uspto-grants-1988_06 |