反应详情

6.1 g of 4-(quinolin-2-yloxy)aniline and 5.8 g of 1,3-dimethyl-5-ethoxycarbonylbarbituric acid are heated under reflux in 50 ml of toluene. When the temperature is at 80° C., a thick crystalline slurry is formed which at 120° C. is again of a stirrable consistency. After stirring for 3 hours, the mixture is cooled and the crystals are isolated by suction filtration.

1. customis at 80° C.
2. customa thick crystalline slurry is formed which at 120° C.
3. temperaturethe mixture is cooled
4. customthe crystals are isolated by suction filtration