HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → HCID 13282892, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | Ethyl 2-(6-fluoro-8-quinolyl)-2-hydroxyacetate | HCID 13560092 | — |
| Product | HCID 13282892 | HCID 13282892 | — |
Reaction Steps
Ethyl 2-(6-fluoro-8-quinolyl)-2-hydroxyacetate (1.1 g.) was refluxed for 10 minutes in 300 ml. of conc. ammonium hydroxide. The reaction mixture was cooled slightly, clarified by filtration and evaporated to solids. Trituration of the residue with 25 ml. of toluene gave the title product (860 mg., m.p. 169°-171° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04753956 |
| Source dataset | uspto-grants-1988_06 |
| ORD ID | ord-67bb7d5391e04f7281a160aaad107862 |
| Source note | uspto-grants-1988_06 |