Morpholine → HCID 54495933, compound

HRID 580606Notes

Reaction equation

HRID 580606 reaction equation
[NH2:1][C:2]1[C:19]([Br:20])=[CH:18][C:5]([C:6]([C:11]2[CH:16]=[CH:15][C:14]([Br:17])=[CH:13][CH:12]=2)=[CH:7][C:8]([OH:10])=O)=[CH:4][C:3]=1[Br:21].ClC(OCC)=O.[NH:28]1[CH2:33][CH2:32][O:31][CH2:30][CH2:29]1>C(N(CC)CC)C>[NH2:1][C:2]1[C:3]([Br:21])=[CH:4][C:5]([C:6]([C:11]2[CH:16]=[CH:15][C:14]([Br:17])=[CH:13][CH:12]=2)=[CH:7][C:8]([N:28]2[CH2:33][CH2:32][O:31][CH2:30][CH2:29]2)=[O:10])=[CH:18][C:19]=1[Br:20]

Participants

5

Reactant 3

HCID 8083MorpholineHCID 10928Ethyl chloroformateHCID 53789063HCID 53789063, compound

Product 1

HCID 54495933HCID 54495933, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

This compound was prepared from 4-amino-β-(4'-bromophenyl)-3,5-dibromo-cinnamic acid (isomer ratio A:B=1.5:1), ethyl chloroformate, triethylamine and morpholine analogous to Example 3.

Sources & evidence

ORD record
ord-ab02ac3276b84890b54eb457ff6da7d9
Source dataset
uspto-grants-1988_06
Patent number
US04753934

Reaction notes

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