反应详情

温度

5 °C

A solution containing 3.5 g of 3,5-dichlorostyrene oxide in 50 ml of absolute ethanol and 20 ml of t-butylamine is heated gently at reflux for 8 hours and the mixture is evaporated to dryness. The clear yellow syrup is dissolved in 75 ml of ethanol and 25 ml of H2O, and the solution is cooled to 5° C. and acidified with 3N HCl. This solution is evaporated to dryness in vacuo and the residual white solid is recrystallized from acetone to afford 2.81 g, m.p. 218°-221° C.

1. temperatureis heated gently
2. temperatureat reflux for 8 hours
3. customthe mixture is evaporated to dryness
4. dissolutionThe clear yellow syrup is dissolved in 75 ml of ethanol
5. customThis solution is evaporated to dryness in vacuo
6. customthe residual white solid is recrystallized from acetone
7. customto afford 2.81 g, m.p. 218°-221° C.