Benzhydrol → Benzophenone

HRID 580689Notes

Reaction equation

HRID 580689 reaction equation
CC(O)CCCCCC.[CH:10]([OH:23])([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[C:10]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)(=[O:23])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 7037BenzhydrolHCID 200832-Octanol

Product 1

HCID 3102BenzophenoneYield 99.4%

Procedure

Example 3 was repeated, replacing catalyst (IV) to 0.69 g (0.25 mmol), of catalyst (V), replacing 2-octanol with 9.20 g (50 mmol) of benzhydrol, and reducing the reaction time to 1 hour. 9.04 g (49.7 mmol) of benzophenone were thus obtained (GCL purity>99%), which corresponds to a 99% yield.

Workup

  1. customto 1 hour

Sources & evidence

ORD record
ord-a737c99e19aa4df0a4902183f3ffd1d0
Source dataset
uspto-grants-1988_06
Patent number
US04754073

Reaction notes

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