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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 580825Generated: October 30, 2026

4-Methoxybenzylamine → HCID 54264880, compound

https://huagongshe.com/reaction/580825

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzylamineHCID 75452—
ReactantHCID 53662505HCID 53662505—
SolventO-XyleneHCID 7237—
ProductHCID 54264880HCID 5426488024.1%

Reaction Conditions

Temperature130 °C

Reaction Steps

A mixture of 4,5-di-(2-chloropyridin-3-yl)thiazole (0.047 g), 4-methoxybenzylamine (0.021 g), and diisopropylethylaamine (0.025 g) in xylene was heated in a sealed tube at 130° C. for 4 days. The solvent was evaporated, and the residue was fractionated by chromatography to give 4-[2-(4-methoxybenzylamino)pyridin-3-yl]-5-(2-chloropyridin-3-yl)thiazole (0.015 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05919779
Source datasetuspto-grants-1999_07
ORD IDord-685566fd1b4b449aaee2cb1e809bc8d2
Source noteuspto-grants-1999_07