HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 580825Generated: October 30, 2026
4-Methoxybenzylamine → HCID 54264880, compound
https://huagongshe.com/reaction/580825
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methoxybenzylamine | HCID 75452 | — |
| Reactant | HCID 53662505 | HCID 53662505 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 54264880 | HCID 54264880 | 24.1% |
Reaction Steps
A mixture of 4,5-di-(2-chloropyridin-3-yl)thiazole (0.047 g), 4-methoxybenzylamine (0.021 g), and diisopropylethylaamine (0.025 g) in xylene was heated in a sealed tube at 130° C. for 4 days. The solvent was evaporated, and the residue was fractionated by chromatography to give 4-[2-(4-methoxybenzylamino)pyridin-3-yl]-5-(2-chloropyridin-3-yl)thiazole (0.015 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05919779 |
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| Source dataset | uspto-grants-1999_07 |
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| ORD ID | ord-685566fd1b4b449aaee2cb1e809bc8d2 |
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| Source note | uspto-grants-1999_07 |
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