HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67689969, compound → HCID 54308048, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67689969 | HCID 67689969 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 54308048 | HCID 54308048 | — |
Reaction Steps
Ethyl 3-[1-tert-butyloxycarbonyl-5-(1,2,4-triazol-1-yl)pyrrolo[2,3-c]pyridin-3-yl]prop-2-enoate (0.29 g) was hydrogenated over palladium on carbon (10%, 0.435 g) in ethanol (50 mL) at 50 psi of hydrogen for 75 min. The catalyst was removed by filtration and the solvent evaporated in vacuo to give the title compound. (0.24 g) as a colourless solid. This was used without further purification in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05919783 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-8b50c08f2153401e95d48742a767375f |
| Source note | uspto-grants-1999_07 |