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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 580849Generated: October 29, 2026

HCID 67689969, compound → HCID 54308048, compound

https://huagongshe.com/reaction/580849

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67689969HCID 67689969—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 54308048HCID 54308048—

Reaction Steps

Ethyl 3-[1-tert-butyloxycarbonyl-5-(1,2,4-triazol-1-yl)pyrrolo[2,3-c]pyridin-3-yl]prop-2-enoate (0.29 g) was hydrogenated over palladium on carbon (10%, 0.435 g) in ethanol (50 mL) at 50 psi of hydrogen for 75 min. The catalyst was removed by filtration and the solvent evaporated in vacuo to give the title compound. (0.24 g) as a colourless solid. This was used without further purification in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05919783
Source datasetuspto-grants-1999_07
ORD IDord-8b50c08f2153401e95d48742a767375f
Source noteuspto-grants-1999_07