Cyclopropanecarbonyl chloride → HCID 19601461, compound

HRID 581337Notes

Reaction equation

HRID 581337 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]2[C:8]([C:11]3[CH2:12][CH2:13][N:14]([CH2:17][CH3:18])[CH2:15][CH:16]=3)=[CH:9][NH:10][C:5]2=[CH:4][CH:3]=1.[CH:19]1([C:22](Cl)=[O:23])[CH2:21][CH2:20]1>>[CH:19]1([C:22]([NH:1][C:2]2[N:7]=[C:6]3[C:8]([C:11]4[CH2:12][CH2:13][N:14]([CH2:17][CH3:18])[CH2:15][CH:16]=4)=[CH:9][NH:10][C:5]3=[CH:4][CH:3]=2)=[O:23])[CH2:21][CH2:20]1

Participants

3

Reactant 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 10922730HCID 10922730, compound

Product 1

HCID 19601461HCID 19601461, compound

Procedure

Beginning with 0.015 gm (0.062 mMol) 5-amino-3-(1-ethyl-1,2,3,6-tetrahydropyridin-4-yl)pyrrolo[3,2-b]pyridine and 0.006 mL (0.068 mMol) cyclopropanecarbonyl chloride, the title compound was prepared essentially by the procedure described in Example 7.

Sources & evidence

ORD record
ord-54dbf6c7899e48558046a759535d186a
Source dataset
uspto-grants-1999_07
Patent number
US05919936

Reaction notes

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