L-Phenylalanine → 2-Phenylethanol

HRID 581469Notes

Reaction equation

N[C@H:2](C(O)=O)[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[OH-:13].[Na+]>>[CH2:2]([OH:13])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

Reactant 2

HCID 6140L-Phenylalanine2×

HCID 14798Sodium Hydroxide

Product 1

HCID 60542-Phenylethanol

Procedure

Referring to FIG. 1, L-phenylalanine is provided as a solution 10, wherein the solution comprises fermentation media 12 containing L-phenylalanine. Alternatively, the fermentation media is combined with a solution of L-phenylalanine. The combined fermentation solution is added 20 to a fermentation bath, which fermentation bath is then inoculated with at least one species of yeast 22. The pH of the fermentation solution is adjusted 40 to a pH of about 7.0 with a base (e.g., NaOH) after which the fermentation solution is allowed to ferment under fermentation conditions 30, providing phenethyl alcohol.

Workup

additionThe combined fermentation solution is added 20 to a fermentation bath

Sources & evidence

ORD record: ord-0c4d5f8de62a45aa875d7c80369a7e3f
Source dataset: uspto-grants-1999_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05919991

Reaction notes

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