Cyclopentanone → methyl 2-(N-tert-butyl-sulfamoyl)-4-cyclopentylidenehydrazinobenzoate

HRID 581657ノート

反応式

HRID 581657 の反応式
[C:1]1(=O)[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:7]([NH:11][S:12]([C:15]1[CH:24]=[C:23]([NH:25][NH2:26])[CH:22]=[CH:21][C:16]=1[C:17]([O:19][CH3:20])=[O:18])(=[O:14])=[O:13])([CH3:10])([CH3:9])[CH3:8]>CO>[C:7]([NH:11][S:12]([C:15]1[CH:24]=[C:23]([NH:25][N:26]=[C:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)[CH:22]=[CH:21][C:16]=1[C:17]([O:19][CH3:20])=[O:18])(=[O:14])=[O:13])([CH3:10])([CH3:8])[CH3:9]

参加物

4

反応物 2

HCID 8452CyclopentanoneHCID 21716182methyl 2-(N-tert-butylsulfamoyl)-4-hydrazinobenzoate

生成物 1

HCID 21716183methyl 2-(N-tert-butyl-sulfamoyl)-4-cyclopentylidenehydrazinobenzoate収率 51%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

反応条件

温度
65 °C

実験手順

2.8 g (0.032 mol) of cyclopentanone are added to 2.0 g (0.007 mol) of methyl 2-(N-tert-butylsulfamoyl)-4-hydrazinobenzoate in 100 ml of methanol and the mixture is subsequently stirred at 65° C. for 3 hours. It is evaporated and the residue is triturated with a little methanol. After filtering off with suction and drying, 1.3 g (51% of theory) of methyl 2-(N-tert-butyl-sulfamoyl)-4-cyclopentylidenehydrazinobenzoate are obtained.

後処理

  1. customIt is evaporated
  2. customthe residue is triturated with a little methanol
  3. filtrationAfter filtering off with suction
  4. customdrying

出典と根拠

ORDレコード
ord-b0dc3e79b5b049a6b7e096c76011bad5
出典データセット
uspto-grants-1999_07
特許番号
US05922645

反応ノート

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