反应详情

50 g (0.335 mol) of 3-(4-pyridyl)-acrylic acid are hydrogenated in 800 ml of 50% strength acetic acid with the addition of 10 g of platinum dioxide as the catalyst at room temperature under a hydrogen pressure of 50 psi until the uptake of hydrogen has ended. After the catalyst has been filtered off, the filtrate is concentrated to dryness in vacuo and the residue which remains is crystallized from a little methanol, after addition of ether.

1. filtrationAfter the catalyst has been filtered off
2. concentrationthe filtrate is concentrated to dryness in vacuo
3. customthe residue which remains is crystallized from a little methanol
4. additionafter addition of ether