Trifluoroacetic acid → HCID 22880364, compound

HRID 581833Notes

Reaction equation

HRID 581833 reaction equation
C(OC([NH:8][C@H:9]([C:11]([N:13]1[CH2:18][CH2:17][CH:16]([O:19][CH2:20][C:21]([O:23][CH3:24])=[O:22])[CH2:15][CH2:14]1)=[O:12])[CH3:10])=O)(C)(C)C.[F:25][C:26]([F:31])([F:30])[C:27]([OH:29])=[O:28]>C(Cl)Cl>[F:25][C:26]([F:31])([F:30])[C:27]([OH:29])=[O:28].[NH2:8][C@H:9]([C:11]([N:13]1[CH2:14][CH2:15][CH:16]([O:19][CH2:20][C:21]([O:23][CH3:24])=[O:22])[CH2:17][CH2:18]1)=[O:12])[CH3:10]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 22880368HCID 22880368, compound

Product 1

HCID 22880364HCID 22880364, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared from methyl N-(tert-butyloxycarbonyl-L-alanyl)-4-piperidinyloxyacetate and trifluoroacetic acid in methylene chloride analogously to Example 2.

Sources & evidence

ORD record
ord-ac64b7b435db4e379bb838dac8052486
Source dataset
uspto-grants-1999_07
Patent number
US05922717

Reaction notes

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