HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 12797183, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-(2-Methyl-1H-imidazol-1-yl)aniline | HCID 12797139 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 12797183 | HCID 12797183 | 97% |
Reaction Steps
3-(2-Methylimidazol-1-yl)aniline (11 g, 63.6 mmol) is added in portions to acetic anhydride (100 ml) at ambient temperature. After stirring for 1 hour the mixture is poured into water (300 ml). The resulting solution is cooled in an ice-bath and rendered alkaline with aqueous sodium hydroxide (12M). The product is filtered off, washed thoroughly with water and dried to yield 2j (12.3 g, 97%). Mp 238-240° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05922724 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-ca98cf5ea6cd43c695501570284bf073 |
| Source note | uspto-grants-1999_07 |