Sulfuric Acid → 1-(4-amino-3-nitrophenyl)ethanone

HRID 581962Notes

Reaction equation

HRID 581962 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10]C(=O)C)=[C:6]([N+:14]([O-:16])=[O:15])[CH:5]=1)(=[O:3])[CH3:2].S(=O)(=O)(O)O>O>[C:1]([C:4]1[CH:9]=[CH:8][C:7]([NH2:10])=[C:6]([N+:14]([O-:16])=[O:15])[CH:5]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 286549n-(4-Acetyl-2-nitrophenyl)acetamide

Product 1

HCID 115863891-(4-amino-3-nitrophenyl)ethanone

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

N-(4-acetyl-2-nitrophenyl)acetamide (26.5 g, 11.94 mmol) was added to a mixture of water and concentrated sulfuric acid, 150 ml (1:2). After 15 minutes the mixture was poured into water. The product was filtered off, washed with water and dried.

Workup

  1. filtrationThe product was filtered off
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-4cd9d2f8740145f98a89fec295a82ac8
Source dataset
uspto-grants-1999_07
Patent number
US05922724

Reaction notes

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