HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 5-Trifluoromethyl-6-methoxybenzo[b]thiophene-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethyl 5-trifluoromethyl-6-methoxybenzo[b]thiophene-3-carboxylate | HCID 53925736 | — |
| Product | 5-Trifluoromethyl-6-methoxybenzo[b]thiophene-3-carboxylic acid | HCID 54077474 | 92% |
Reaction Steps
Ethyl 5-trifluoromethyl-6-methoxybenzo[b]thiophene-3-carboxylate (D6) (0.5 g, 2 mmoles) was treated with sodium hydroxide as in the method of description 5 to give the title compound (D7) (0.42 g, 92%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05922733 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-2b20f271724b47dabebac6679b357d37 |
| Source note | uspto-grants-1999_07 |