HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Piperidinecarboxylic acid, 4-(1H-benzimidazol-2-ylamino)-, ethyl ester → (1-(2-(2,2,2-trifluoroethoxy)ethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Piperidinecarboxylic acid, 4-(1H-benzimidazol-2-ylamino)-, ethyl ester | HCID 3018455 | — |
| Reactant | 2-Methanesulfonyloxyethyl 2,2,2-trifluorethyl ether | HCID 18673718 | — |
| Product | (1-(2-(2,2,2-trifluoroethoxy)ethyl)-1H-benzimidazol-2-yl)(piperidin-4-yl)amine | HCID 22009486 | — |
Reaction Steps
Prepare by the method of Preparation 14 using 2-methanesulfonyloxyethyl 2,2,2-trifluoroethyl ether and (1H-benzimidazol-2-yl)(1-ethoxycarbonylpiperidin-4-yl)amine to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05922737 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-5831e1c1fd1f43e6be799f6d335bff53 |
| Source note | uspto-grants-1999_07 |