反应详情

温度

105 °C

In 25 ml of n-butanol were dissolved 26.9 g (0.1 mols) of the purified product of 2-(2H-benzotriazole-2-yl)-4-(3-hydroxypropyl)phenol synthesized in Example 8, 5.2 g of 80% paraformaldehyde and 11.0 g (0.15 mols) of diethylamine. The solution was refluxed with heating at 105° C. for 24 hours. After completion of the reaction, the solvent and remaining raw materials were collected under reduced pressure, giving 35.9 g of objective 2-(2H-benzotriazole-2-yl)-4-(3-hydroxypropyl)-6-(N,N-diethylaminomethyl)phenol as a brown oil (yield 97.0%, purity 95.6%).

1. temperatureThe solution was refluxed
2. customAfter completion of the reaction
3. customwere collected under reduced pressure