Hydride → HCID 11528574, compound

HRID 582287Notes

Reaction equation

HRID 582287 reaction equation
[CH3:1][CH:2]1[CH2:11][C:10]2[C:5](=[C:6]([O:15][CH3:16])[C:7]([CH3:14])=[C:8]([O:12]C)[CH:9]=2)[CH2:4][O:3]1.[H-]>CN(C=O)C>[CH3:1][CH:2]1[CH2:11][C:10]2[C:5](=[C:6]([O:15][CH3:16])[C:7]([CH3:14])=[C:8]([OH:12])[CH:9]=2)[CH2:4][O:3]1

Participants

4

Reactant 2

HCID 166653HydrideHCID 11020468HCID 11020468, compound

Product 1

HCID 11528574HCID 11528574, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A method for synthesizing isochromans comprising reacting 3,7-dimethyl-6,8-dimethoxyisochroman with sodium ethyl thiolate or hydride reagents in DMF to produce 3,7-dimethyl-6-hydroxy-8-methoxyisochroman.

Sources & evidence

ORD record
ord-900845309e734d89b7eebc982e8dd9da
Source dataset
uspto-grants-1999_07
Patent number
US05922889

Reaction notes

Loading…