HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-(+)-1-Aminopropan-2-ol → HCID 86754239, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-(+)-1-Aminopropan-2-ol | HCID 7311736 | — |
| Reactant | 4-[1-[3-(Isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzoic acid methyl ester | HCID 53711670 | — |
| Product | HCID 86754239 | HCID 86754239 | 81% |
Reaction Steps
By the same procedure as described in the example 31, synthesis was carried out starting with 4-[1-[3-(isopropylamino)-2-pyridyl]piperazin-4-yl-carbonyl]benzoic acid methyl ester and using (S)-(+)-1-amino-2-propanol. Then, the product was recrystallized using isopropanol and tetrahydrofuran to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05922871 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-d7eeef956b204721a137a836e61d7e13 |
| Source note | uspto-grants-1999_07 |