Hydrochloric Acid → HCID 19598108, compound

HRID 582364Notes

Reaction equation

HRID 582364 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:14][CH3:15])=[C:6]([C:12]=1[Cl:13])[C:7]([O:9]CC)=[O:8].C(O)C.[OH-].[Na+].Cl>O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:14][CH3:15])=[C:6]([C:12]=1[Cl:13])[C:7]([OH:9])=[O:8]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 14798Sodium HydroxideHCID 19598109HCID 19598109, compound

Product 1

HCID 19598108HCID 19598108, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A mixture of 4A (1.7 g, 5.8 mmol), water (10 ml), ethanol (20 ml) and sodium hydroxide (0.5 g, 12.5 mmol) is heated under reflux with stirring. The reaction mixture is diluted with water (80 ml) and acidified with concentrated hydrochloric acid. The solid material is collected by filtration, washed with water and dried yielding white crystals, 1.3 g (85%), mp 186-188° C.

Workup

  1. temperatureis heated
  2. temperatureunder reflux
  3. filtrationThe solid material is collected by filtration
  4. washwashed with water
  5. customdried
  6. customyielding white crystals, 1.3 g (85%), mp 186-188° C.

Sources & evidence

ORD record
ord-64c7da5bfdb241b0b434c4ddfb855e9e
Source dataset
uspto-grants-1999_07
Patent number
US05922905

Reaction notes

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