Barium Sulfate → HCID 53945408, compound

HRID 582611Notes

Reaction equation

HRID 582611 reaction equation
[C:1]([CH2:3][CH2:4][CH:5]1[CH2:10][CH2:9][C:8]2[CH:11]=[C:12]([N+:15]([O-])=O)[CH:13]=[CH:14][C:7]=2[O:6]1)#[N:2].S([O-])([O-])(=O)=O.[Ba+2]>O1CCCC1.[Pd]>[C:1]([CH2:3][CH2:4][CH:5]1[CH2:10][CH2:9][C:8]2[CH:11]=[C:12]([NH2:15])[CH:13]=[CH:14][C:7]=2[O:6]1)#[N:2]

Participants

5

Reactant 2

HCID 24414Barium SulfateHCID 53782106HCID 53782106, compound

Product 1

HCID 53945408HCID 53945408, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

A solution of 4.3 g (18.5 mmol) of 2-cyanoethyl-6-nitro-3,4-dihydro-2H-1-benzopyran in 80 ml of tetrahydrofuran is hydrogenated in the presence of 1 g of palladium on 5% barium sulfate. The mixture is stirred for 2 days, then it is filtered and the filtrate is concentrated under reduced pressure. By chromatography of the residue on a silica column using cyclohexane containing 30% ethyl acetate, 2.5 g of product are obtained.

Workup

  1. filtrationit is filtered
  2. concentrationthe filtrate is concentrated under reduced pressure
  3. customare obtained

Sources & evidence

ORD record
ord-a7623dca88064f6bbe4e1fe9b9d909d7
Source dataset
uspto-grants-1999_07
Patent number
US05925662

Reaction notes

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