Ethyl chloroformate → HCID 54177198, compound

HRID 582612Notes

Reaction equation

HRID 582612 reaction equation
[C:1]([CH2:3][CH2:4][CH:5]1[CH2:10][CH2:9][C:8]2[CH:11]=[C:12]([NH2:15])[CH:13]=[CH:14][C:7]=2[O:6]1)#[N:2].Cl[C:17]([O:19][CH2:20][CH3:21])=[O:18].C(=O)([O-])O.[Na+]>>[C:1]([CH2:3][CH2:4][CH:5]1[CH2:10][CH2:9][C:8]2[CH:11]=[C:12]([NH:15][C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:13]=[CH:14][C:7]=2[O:6]1)#[N:2]

Participants

4

Reactant 3

HCID 10928Ethyl chloroformateHCID 516892Sodium BicarbonateHCID 53945408HCID 53945408, compound

Product 1

HCID 54177198HCID 54177198, compound

Procedure

By a process analogous to that of step 6 of Example 1, starting from 2.4 g (12 mmol) of 2-cyanoethyl-6-amino-3,4-dihydro-2H-1-benzopyran, 1.24 ml (13.0 mmol) of ethyl chloroformate and 1.5 g (18 mmol) of sodium hydrogencarbonate, 2.0 g of product are obtained.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-fa429c6ffaed492390c957552fb2f8f3
Source dataset
uspto-grants-1999_07
Patent number
US05925662

Reaction notes

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