HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Cyanide → 2-Cyanoethyl-2,3-dihydrobenzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Cyanide | HCID 9032 | — |
| Reactant | 2-(2-Tosyloxyethyl)-2,3-dihydrobenzofuran | HCID 54469994 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-Cyanoethyl-2,3-dihydrobenzofuran | HCID 54456438 | 92.6% |
Reaction Steps
Starting from 15.2 g (48 mmol) of 2-p-toluenesulfonyloxyethyl-2,3-dihydrobenzofuran (compound described in the U.S. Pat. No. 4,129,655) and 3.4 g (52 mmol) of potassium cyanide in 170 ml of dimethyl sulfoxide treated under the conditions described in step 5 of Example 7, 7.7 g of product were obtained in oil form.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05925662 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-eeecebefe8444e3d92f5801d1b46557b |
| Source note | uspto-grants-1999_07 |