Sodium Nitrate → HCID 53782759, compound

HRID 582614Notes

Reaction equation

HRID 582614 reaction equation
[C:1]([CH2:3][CH2:4][CH:5]1[CH2:9][C:8]2[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=2[O:6]1)#[N:2].[N+:14]([O-])([O-:16])=[O:15].[Na+]>FC(F)(F)C(O)=O>[C:1]([CH2:3][CH2:4][CH:5]1[CH2:9][C:8]2[CH:10]=[C:11]([N+:14]([O-:16])=[O:15])[CH:12]=[CH:13][C:7]=2[O:6]1)#[N:2]

Participants

4

Reactant 2

HCID 24268Sodium NitrateHCID 544564382-Cyanoethyl-2,3-dihydrobenzofuran

Product 1

HCID 53782759HCID 53782759, compoundYield 36.2%

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

Starting from 7.5 g (43 mmol) of 2-cyanoethyl-2,3-dihydrobenzofuran in 120 ml of trifluoroacetic acid and 11 g (130 mmol) of sodium nitrate treated under the conditions described in step 6 of Example 7, 3.4 g of product were obtained.

Workup

  1. additiontreated under the conditions

Sources & evidence

ORD record
ord-46bc941cd41e4109a40ad5e9c491371d
Source dataset
uspto-grants-1999_07
Patent number
US05925662

Reaction notes

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