HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → [1(R) Methyl-2-(pyridin-2-yl)ethyl]carbamic acid trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | [1(R) Methyl-2-(pyridin-2-yl)ethyl]carbamic acid t-butylester | HCID 131721312 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | [1(R) Methyl-2-(pyridin-2-yl)ethyl]carbamic acid trifluoroacetate | HCID 86754265 | — |
Reaction Steps
TFA (4 mL) was added to a CH2Cl2 solution (10 mL) of 7-3 (120 mg, 0.48 mmol) and the solution stirred under ambient conditions for 2 h and concentrated to dryness. The residue was azeotroped with toluene (3×25 mL) to provide 7-4 as a light-yellow semi-solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05925655 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-82cad64b667244688802d5090f7786b9 |
| Source note | uspto-grants-1999_07 |