HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → 3-Methyl-N-phenylbutanimidic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-Isopropylaniline | HCID 12561 | — |
| Product | 3-Methyl-N-phenylbutanimidic acid | HCID 222941 | — |
Reaction Steps
A mixture containing 300 ml of toluene and 31 ml of 2-isopropylaniline is cooled in ice, and 22 ml of acetic anhydride are added slowly. After 40 minutes with stirring at RT, the reaction medium is evaporated and the residue is then taken up with petroleum ether. The precipitate formed is drained. 35.9 g of the expected product are obtained after crystallization in petroleum ether, m.p.=81° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05925661 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-bd9c4bb791a64485a23ba2fe76eab398 |
| Source note | uspto-grants-1999_07 |