HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → 2-[5-(2,6-Dimethoxyphenyl)-1-[4-[N-methyl-N-(3-dimethylaminopropyl)carbamoyl]-2-isopropylphenyl]-3-pyrazolylcarbonylamino]-2-adamantanecarboxylic acid benzenesulphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Benzenesulfonic Acid | HCID 7371 | — |
| Reactant | SR142948A | HCID 5311451 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-[5-(2,6-Dimethoxyphenyl)-1-[4-[N-methyl-N-(3-dimethylaminopropyl)carbamoyl]-2-isopropylphenyl]-3-pyrazolylcarbonylamino]-2-adamantanecarboxylic acid benzenesulphonate | HCID 86754283 | 9.8% |
Reaction Steps
A mixture of 0.5 g of the compound obtained in EXAMPLE 1' and 0.16 g of benzenesulphonic acid in 5 ml of MeOH is poured. into 75 ml of ether cooled to 5° C., and the precipitate formed is drained. 0.06 g of the expected product is obtained, m.p.=170° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05925661 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-fa26715391c84d6d8b6ebccfad6dab24 |
| Source note | uspto-grants-1999_07 |