HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N-(2-Methylcyclohex-1-yl)-1-(3-chloro-4-methylbenzyl)-5-(3,4-dichlorophenyl)pyrazole-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Methylcyclohexylamine | HCID 23432 | — |
| Reactant | 1-(3-Chloro-4-methylbenzyl)-5-(3,4-dichlorophenyl)pyrazole-3-carboxylic acid chloride | HCID 54095265 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(2-Methylcyclohex-1-yl)-1-(3-chloro-4-methylbenzyl)-5-(3,4-dichlorophenyl)pyrazole-3-carboxamide | HCID 53722250 | — |
Reaction Steps
This compound is prepared by the procedure described in step B of EXAMPLE 36 from 1 ml of 2-methylcyclohexylamine, 1 ml of triethylamine in 15 ml of DCM and 1.5 g of the compound obtained in step A of EXAMPLE 36 in 15 ml of DCM. The compound is purified by chromatography on silica using a DCM/MeOH mixture (98/2; v/v) as the eluent to give 0.27 g of the expected product. M.p.=165° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05925768 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-7df87266b2ea4008874eef01edf3aabf |
| Source note | uspto-grants-1999_07 |