HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N-(2,6-Dimethylcyclohex-1-yl)-1-(3-chloro-4-methylbenzyl)-5-(3,4-dichlorophenyl)pyrazole-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,6-Dimethylcyclohexan-1-amine hydrochloride | HCID 22250942 | — |
| Reactant | 1-(3-Chloro-4-methylbenzyl)-5-(3,4-dichlorophenyl)pyrazole-3-carboxylic acid chloride | HCID 54095265 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(2,6-Dimethylcyclohex-1-yl)-1-(3-chloro-4-methylbenzyl)-5-(3,4-dichlorophenyl)pyrazole-3-carboxamide | HCID 54139641 | 32.8% |
Reaction Steps
This compound is prepared by the procedure described in step B of EXAMPLE 36 from 0.605 g of 2,6-dimethylcyclohexylamine hydrochloride, 1 ml of triethylamine in 15 ml of DCM and 1.5 g of the compound obtained in step A of EXAMPLE 36 in 15 ml of DCM. 0.6 g of the expected product is obtained; m.p.=59.9° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05925768 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-7cec936df46141748d1a055deabda09c |
| Source note | uspto-grants-1999_07 |