反应详情

温度

120 °C

The title compound was prepared essentially as in Example 1 by combining 3-(2-(2-(2-(trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)-1-chloropropane (5.2 g, 10.9 mmol, Example 24) with 5-octyloxy-2-(4-hydroxyphenyl)pyrimidine (3 g, 10.0 mmol) in dimethylformamide and stirring at 120° C. overnight. The resulting product was further purified by Kugelrohr distillation (b.p. 195-210° C. at 0.3 torr), followed by recrystallization from ethanol and additional distillation (yield of 3.5 g).

1. distillationThe resulting product was further purified by Kugelrohr distillation (b.p. 195-210° C. at 0.3 torr)
2. customfollowed by recrystallization from ethanol and additional distillation (yield of 3.5 g)