HCID 21225311, compound → HCID 21225413, compound

Participants

Reaction Steps

The title compound was prepared essentially as in Example 1 by combining 3-(2,2,3,3,4,4,4-heptafluorobutoxy)propyl chloride (4.1 g of 68% purity, 10.7 mmol, prepared from 1,3-dichloropropane and 2,2,3,3,4,4,4-heptafluorobutanol) with 5-decyloxy-2-(4-hydroxyphenyl)pyrimidine (3.5 g, 10.7 mmol). The resulting crude product was isolated essentially as described in Example 3 and purified by chromatography on silica gel, eluting with 10 vol. % ethyl acetate in hexane, followed by Kugelrohr distillation (220° C. at 0.5 torr) to provide a yield of 4.8 g.

Provenance & Evidence