m-Chloroperbenzoic acid → HCID 21226437, compound

HRID 583044Notes

Reaction equation

HRID 583044 reaction equation
ClC1C=CC=C(C(OO)=[O:9])C=1.[Cl:12][C:13]1[C:14]([C:23]2[CH:28]=[CH:27][C:26]([Cl:29])=[C:25]([CH2:30][S:31][CH2:32][CH3:33])[CH:24]=2)=[N:15][N:16]([CH3:22])[C:17]=1[O:18][CH:19]([F:21])[F:20]>ClCCl>[Cl:12][C:13]1[C:14]([C:23]2[CH:28]=[CH:27][C:26]([Cl:29])=[C:25]([CH2:30][S:31]([CH2:32][CH3:33])=[O:9])[CH:24]=2)=[N:15][N:16]([CH3:22])[C:17]=1[O:18][CH:19]([F:21])[F:20]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 21226439HCID 21226439, compound

Product 1

HCID 21226437HCID 21226437, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1.4 g (4 mmol) of m-chloroperbenzoic acid were added a little at a time at 0° C. to a solution of 1.5 g (4 mmol) of 4-chloro-3-[4-chloro-3-(ethylthiomethyl)phenyl]-5-difluoromethoxy-1-methyl-1H-pyrazole in 40 ml of dichloromethane. The mixture was stirred at 0° for 30 minutes was subsequently stirred at room temperature for 4 hours and then the solids were removed by filtration. The filtrate was concentrated, and the crude product thus obtained was purified by chromatography on silica gel (eluent: hexane/ethyl acetate=1:1). Yield: 0.2 g.

Workup

  1. stirringwas subsequently stirred at room temperature for 4 hours
  2. customthe solids were removed by filtration
  3. concentrationThe filtrate was concentrated

Sources & evidence

ORD record
ord-383fdeb4679d43acbc551f1e4c9c5c77
Source dataset
uspto-grants-1999_07
Patent number
US05928999

Reaction notes

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