Chloroform → HCID 21584181, compound

Participants

Reaction Steps

A mixture comprising 163 mg of 4-bromo-5-[3-{2-(4-(4-chlorobenzyl)-piperazin-1-yl)-ethoxy}-4-methoxybenzylamino]-3(2H)-pyridazinone, 33 mg of fumaric acid and 4 ml of chloroform, was stirred at room temperature for 3 hours. Diethyl ether was added to the reaction solution for crystallization to obtain 120 mg of the above-identified compound as white crystals having a melting point of from 178-185° C.

Provenance & Evidence