HCID 53908716, compound → HCID 67637613, compound

Participants

Reaction Steps

This material was made by hydrogenation with H2 in methanol over 20% palladium hydroxide of 6-(4-fluorophenyl)-3-[3-methoxy-6-(5-trifluoromethyl-tetrazol-1-yl)-pyridin-2-yl]-1-oxaspiro[4.4]non-3-ene-7-carboxylic acid methyl ester by the method given in Example 6, Step G. NMR (400 MHz, CDCl3): δ 7.66(d, J=7Hz,1H); 7.29(m, 3H); 6.90(t, J=9 Hz, 2H); 4.1(t, J=7Hz, 1H); 3.88 (s over multiplet, 3H+1H); 3.54(s,3H); 3.2-3.35(m, 3H); 2.25-2.33(m, 1H); 2.1-2.22(m, 3H); 1.90-2.0(m, 2H); Mass spectrum: 522 (M+1).

Provenance & Evidence