Ammonium Hydroxide → HCID 15407444, compound

HRID 583231Notes

Reaction equation

HRID 583231 reaction equation
[CH3:1][CH:2]1[CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[N:3]1.[N+:12]([O-])([O-:14])=[O:13].[K+].[OH-].[NH4+]>S(=O)(=O)(O)O>[CH3:1][CH:2]1[CH2:11][C:10]2[C:5](=[CH:6][C:7]([N+:12]([O-:14])=[O:13])=[CH:8][CH:9]=2)[CH:4]=[N:3]1

Participants

5

Reactant 3

HCID 14923Ammonium HydroxideHCID 24434Potassium NitrateHCID 152540493,4-Dihydro-3-methylisoquinoline

Product 1

HCID 15407444HCID 15407444, compound

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

3-Methyl-3,4-dihydroisoquinoline (7.0 g, 48.2 mmol) was dissolved in concentrated sulfuric acid (150 ml) and to this was added potassium nitrate (4.9 g, 50.0 mmol). The mixture was allowed to stir overnight, dumped onto ice, and neutralized with the addition of concentrated ammonium hydroxide. The precipated solids were collected by filtration, washed, and air-dried: 7.5 g (82%), m.p. 110-2° C.

Workup

  1. filtrationThe precipated solids were collected by filtration
  2. washwashed
  3. customair-dried

Sources & evidence

ORD record
ord-1ec2fded24094947bb3b87d23abbe4d4
Source dataset
uspto-grants-1999_07
Patent number
US05929085

Reaction notes

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