HCID 70126930, compound → HCID 70128349, compound

HRID 583265Notes

Reaction equation

HRID 583265 reaction equation
[ClH:1].[N+:2]([C:5]1[CH:16]=[CH:15][C:8]2[N:9]([CH3:14])[CH2:10][CH2:11][NH:12][CH2:13][C:7]=2[CH:6]=1)([O-])=O>CO>[ClH:1].[NH2:2][C:5]1[CH:16]=[CH:15][C:8]2[N:9]([CH3:14])[CH2:10][CH2:11][NH:12][CH2:13][C:7]=2[CH:6]=1

Participants

3

Reactant 1

HCID 70126930HCID 70126930, compound

Product 1

HCID 70128349HCID 70128349, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

7-Nitro-1-methyl-3,4-dihydro-1H-benzo[e][1,4]diazapine hydrochloride (3.2 g, 13.1 mmol) was dissolved in methanol (100 ml) and hydrogenated at 50 psi in the presence of a catalytic quantity of 10% Pd--C. After 1 h the mixture was filtered through glass and evaporated to an oil which was used immediately in the next reaction.

Workup

  1. filtrationAfter 1 h the mixture was filtered through glass
  2. customevaporated to an oil which
  3. customwas used immediately in the next reaction

Sources & evidence

ORD record
ord-b8e2b672372e4569a501828a69243423
Source dataset
uspto-grants-1999_07
Patent number
US05929085

Reaction notes

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