反应详情

To a solution of 1-methyl-7-nitro-3,4-dihydroisoquinoline (3.97 g, 20.9 mmol) in methanol (80 ml) was added sodium borohydride (0.87 g, 23.0 mmol) portionwise. The mixture was stirred for 30 min., acidified with 6N HCl, the solvent was evaporated and the solid was stirred in isopropanol, collected and washed with ether: 5.33 g (>100%); MS (M+H)+ 193.

1. customthe solvent was evaporated
2. stirringthe solid was stirred in isopropanol
3. customcollected
4. washwashed with ether