HCID 70055432, compound → HCID 21310911, compound

HRID 583318Notes

Reaction equation

HRID 583318 reaction equation
C([O:8][C:9](=[O:37])[C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([O:16][CH3:17])[C:11]=1[N:18]([CH2:30][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)[S:19]([C:22]1[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=1)(=[O:21])=[O:20])C1C=CC=CC=1>C(Cl)Cl.CCCCCC>[CH2:30]([N:18]([S:19]([C:22]1[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=1)(=[O:21])=[O:20])[C:11]1[C:12]([O:16][CH3:17])=[CH:13][CH:14]=[CH:15][C:10]=1[C:9]([OH:37])=[O:8])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1

Participants

3

Reactant 1

HCID 70055432HCID 70055432, compound

Product 1

HCID 21310911HCID 21310911, compoundYield 90.3%

Reagents, catalysts & solvents 1

HCID 21226440Methylenechloride HexaneSolvent

Procedure

In the same manner as described in Example 19, 1.86 g (3.6 mmol) of the product of Example 97 provided 1.39 g (90%) of the desired carboxylic acid as a white solid after trituration with CH2Cl2 :hexane (1:4). CI Mass Spec 428.1 (M+H).

Sources & evidence

ORD record
ord-6731f8045e084cdeb51a71993589f12f
Source dataset
uspto-grants-1999_07
Patent number
US05929097

Reaction notes

Loading…