1,3-Dibromopropane → HCID 70054563, compound

HRID 583341Notes

Reaction equation

HRID 583341 reaction equation
[CH3:1][O:2][C:3](=[O:23])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([OH:10])[C:5]=1[NH:11][S:12]([C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)(=[O:14])=[O:13].Br[CH2:25][CH2:26][CH2:27]Br>>[CH3:1][O:2][C:3]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]2[O:10][CH2:27][CH2:26][CH2:25][N:11]([S:12]([C:15]3[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=3)(=[O:13])=[O:14])[C:5]=12)=[O:23]

Participants

3

Reactant 2

HCID 80011,3-DibromopropaneHCID 54048961HCID 54048961, compound

Product 1

HCID 70054563HCID 70054563, compoundYield 46.4%

Procedure

In the same manner as described in Example 159, 0.300 g (0.890 mmol) of the product of Example 31 and 0.127 mL (1.246 mmol) of 1,3-dibromopropane provided 0.156 g (46%) of the desired product as a colorless oil. Electrospray Mass Spec: 378 (M+H).

Sources & evidence

ORD record
ord-8f8a8b52a4924f3a8f658c6bf7d88173
Source dataset
uspto-grants-1999_07
Patent number
US05929097

Reaction notes

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