HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 86752445, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 86752444 | HCID 86752444 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86752445 | HCID 86752445 | — |
Reaction Steps
Ester 21-5 (200 mg, 0.377 mmol) was dissolved in 2 mL CH2Cl2, and 2 ml TFA was added. After 4 h at RT the mixture was concentrated, azeotroped with toluene, and purified by flash chromatography (silica, 28:10:1:1 EtOAc/EtOH/NH4OH/H2O) providing 21-6 as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05929120 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-dbe666bb4de845f88ca8e3ffd667dafb |
| Source note | uspto-grants-1999_07 |