Hydrochloric Acid → HCID 86752447, compound

HRID 583684Notes

Reaction equation

HRID 583684 reaction equation
C([O:5][C:6](=[O:40])[C@@H:7]([NH:30][S:31]([C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)(=[O:33])=[O:32])[CH2:8][NH:9][C:10](=[O:29])[C:11]1[CH:16]=[CH:15][C:14]([O:17][CH2:18][C@@H:19]([NH:21]C(OC(C)(C)C)=O)[CH3:20])=[CH:13][CH:12]=1)(C)(C)C.[ClH:41]>O1CCOCC1>[ClH:41].[NH2:21][C@@H:19]([CH3:20])[CH2:18][O:17][C:14]1[CH:15]=[CH:16][C:11]([C:10]([NH:9][CH2:8][C@H:7]([NH:30][S:31]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)(=[O:33])=[O:32])[C:6]([OH:40])=[O:5])=[O:29])=[CH:12][CH:13]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86752446HCID 86752446, compound

Product 1

HCID 86752447HCID 86752447, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

22-5 (545 mg, 0.94 mmol) in 6N HCl (25 mL) and dioxane (25 mL) was stirred overnight at ambient temperature. Concentration followed by trituration with ether gave 22-6 as a colorless solid.

Workup

  1. concentrationConcentration

Sources & evidence

ORD record
ord-44232965c942453fbee8162dbac2ff95
Source dataset
uspto-grants-1999_07
Patent number
US05929120

Reaction notes

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