HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 4-(Carboxymethoxy)-benzoic acid 1-methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Methyl 4-(t-butyloxyacetyloxy)benzoate | HCID 18928531 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(Carboxymethoxy)-benzoic acid 1-methyl ester | HCID 13816151 | — |
Reaction Steps
Ester 24-1 was dissolved in 15 mL CH2Cl2, then 15 mL TFA was added. After 2 h, the mixture was concentrated providing 24-2 as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05929120 |
| Source dataset | uspto-grants-1999_07 |
| ORD ID | ord-e833d6ddcd4f4fd9a9095b68559d58ac |
| Source note | uspto-grants-1999_07 |