Ammonia → HCID 54346156, compound

HRID 583714Notes

Reaction equation

HRID 583714 reaction equation
[CH3:1][O:2][C:3](=[O:27])[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]([NH:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[N+:24]([O-])=O)=[S:16])=[CH:6][CH:5]=1.N>[Pd].CO>[CH3:1][O:2][C:3](=[O:27])[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][CH2:12][CH2:13][NH:14][C:15]([NH:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[NH2:24])=[S:16])=[CH:6][CH:5]=1

Participants

5

Reactant 2

HCID 222AmmoniaHCID 54203402HCID 54203402, compound

Product 1

HCID 54346156HCID 54346156, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A methanol solution (150 mL) of 36-3 (3.15 g, 8.08 mmol) was saturated with NH3. 10% Pd/C (2 g) was added and the mixture hydrogenated at 1 atm for 4 h. Filtration and concentration provided 36-4 as a purple solid.

Workup

  1. filtrationFiltration and concentration

Sources & evidence

ORD record
ord-531d8f6cb7184f21ba5d3658394f0835
Source dataset
uspto-grants-1999_07
Patent number
US05929120

Reaction notes

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