反应详情

Olefin 45 (1.3.6 g, 2.70 mmol) was dissolved in 40 mL of EtOAc. 10% palladium on carbon catalyst was added (25%) and the reaction mixture was subjected to hydrogenation at rt and atmospheric pressure for 18 h before being filtered through celite and concentrated in vacuo to yield a brown solid, 1.36 g, 100%. m.p. 225-228° C.

1. customwas subjected to hydrogenation at rt
2. filtrationatmospheric pressure for 18 h before being filtered through celite and
3. concentrationconcentrated in vacuo
4. customto yield a brown solid, 1.36 g, 100%