Iodoethane → 1-(3-Chloro-5-trifluoromethyl-phenyl)-4-ethyl-piperazine

HRID 584050Notes

Reaction equation

HRID 584050 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.I[CH2:19][CH3:20]>>[Cl:1][C:2]1[CH:3]=[C:4]([N:12]2[CH2:17][CH2:16][N:15]([CH2:19][CH3:20])[CH2:14][CH2:13]2)[CH:5]=[C:6]([C:8]([F:10])([F:11])[F:9])[CH:7]=1

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 223451951-(3-Chloro-5-(trifluoromethyl)phenyl)piperazine

Product 1

HCID 223452151-(3-Chloro-5-trifluoromethyl-phenyl)-4-ethyl-piperazine

Procedure

Beginning with 1-(3-Chloro-5-trifluoromethyl-phenyl)-piperazine and iodoethane, the title compound was recovered by the procedure described in Example 2. MS m/z (rel. intensity, 70 eV)) 292 (M+, bp), 277 (88), 234 (33), 206 (55), 179 (49).

Workup

  1. customthe title compound was recovered by the procedure

Sources & evidence

ORD record
ord-b4776e9ac77042b9b04afcee885e8566
Source dataset
uspto-grants-2005_08
Patent number
US06924374B2

Reaction notes

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