Hydrochloric Acid → Venlafaxine Hydrochloride

HRID 584143Notes

Reaction equation

HRID 584143 reaction equation
[CH3:1][N:2]([CH2:4][CH:5]([C:14]1([OH:20])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1)[C:6]1[CH:7]=[CH:8][C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:3].[ClH:21]>>[CH3:1][N:2]([CH2:4][CH:5]([C:14]1([OH:20])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1)[C:6]1[CH:7]=[CH:8][C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:3].[ClH:21]

Participants

3

Procedure

The solid venlafaxine is further reacted with hydrochloric acid and crystallized to yield an essentially pure venlafaxine hydrochloride.

Workup

  1. customcrystallized

Sources & evidence

ORD record
ord-5a81fd71222940d4a9c5ab8171fdbb20
Source dataset
uspto-grants-2005_08
Patent number
US06924393B2

Reaction notes

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